In dna, a purine must always pair with a pyrimidine and vice versa in order to ensure that11/29/2023 ![]() The stationarity indices (STIs) can be used to test the validity of the equilibrium assumption. ![]() To this aim, we introduce 2 sets of indices that can be calculated from the nucleotide distribution and the substitution rates. Although these models give meaningful results when applied to biological data, it is not clear if the 2 assumptions mentioned above hold and, if not, how much sequence evolution processes deviate from them. Markov models describing the evolution of the nucleotide substitution process, widely used in phylogeny reconstruction, usually assume the hypotheses of stationarity and time reversibility.
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |